We have just awarded funding to Margot Mayer-Proschel, PhD at the University of Rochester to characterize a new mouse model that her lab has developed for A-T. Previous A-T mouse models have been useful for studying the biochemical, cancer, and immunological problems associated with A-T but haven’t had the brain degeneration and loss of muscle … Read More
On February 28, friends and families of A-T kids across the U.S. and Canada raised funds for A-T research by celebrating Rare Disease Day, as part of the Global Genes Project’s Jeans for Genes program, a national effort to increase awareness for the more than 7,000 rare diseases that affect children. A-T Children’s Project volunteers … Read More
The A-T CureTeam weekend from January 11-13 proved to be a huge success – for both crossing finish lines and raising funds. In total, the 2012 A-T CureTeam runners raised $781,784 for A-T research. At a pasta dinner, A-TCP volunteer President and Co-founder Brad Margus promised a crowd of over 500 runners and supporters that … Read More
Tuesday, November 13 – Thursday, November 15, 2012 Hyatt Dulles – Executive Meeting Center 2300 Dulles Corner Blvd., Herndon, VA Near Dulles International Airport in the Washington DC area Panelists: Krystof Bankiewicz, MD PhD – University of California, San Francisco David Cox, MD PhD – Pfizer Tom Crawford, MD – Johns Hopkins Hospital Shyamal Desai, … Read More
With funding from the A-T Children’s Project and the Australian-based BrAshA-T organization, a team of researchers in Australia is using neuroimaging technology to learn more about abnormal circuitry and inflammation in the brains of A-T patients, possibly providing clues for therapeutic targets and uncovering imaging biomarkers for use in clinical trials. Stephen Rose, PhD, Kate … Read More
The A-T Children’s Project welcomes Dr. Philip LoGrasso to its Scientific Advisory Board. Dr. LoGrasso is a Professor in the Molecular Therapeutics Department and Senior Director of Drug Discovery in the Translational Research Institute within The Scripps Research Institute where he has been since 2005. He current serves on the Scientific Advisory Board for Envoy … Read More
With help from scientists who specialize in brain imaging, the A-T Children’s Project is seeking ways to treat the abnormal brain circuitry in ataxia-telangiectasia (A-T). For the first time, a comprehensive PET and fMRI study of the brains of adults with A-T has begun. PET stands for Positron Emission Tomography, and these scans give three … Read More
Three papers have been published recently in the scientific literature describing: 1) gastrostomy tube (G-tube) safety and satisfaction in patients with A-T; 2) the care of critically ill A-T patients and 3) the care of patients with A-T undergoing operations and the possible risks associated with the use of anesthesia for surgical procedures. G-Tube Placement … Read More
The A-T Children’s Project has granted funding for Yang Xu, PhD from the University of California, San Diego to continue development of a stem cell-based model for A-T. This type of “disease-in-a-dish” model can be used to screen hundreds of thousands of compounds for their ability to diminish or reverse certain characteristics of the disease … Read More
Benjamin Siddoway, PhD from the Louisiana State University (LSU) Health Sciences Center is the first recipient of the A-T Children’s Project’s Post Doctoral Fellowship Award for his grant entitled “Addressing neurological dysfunction in A-T: Investigation into novel, physiologic ATM activation in neurons and ATM-PP1 signaling in reorganization and refinement of post synaptic architecture.” The A-T … Read More
