A-TCP SUPPORTERS CELEBRATE RARE DISEASE DAY

On February 28, friends and families of A-T kids across the U.S. and Canada raised funds for A-T research by celebrating Rare Disease Day, as part of the Global Genes Project’s Jeans for Genes program, a national effort to increase awareness for the more than 7,000 rare diseases that affect children. A-T Children’s Project volunteers … Read More

GLOBAL A-T NEUROSCIENCE AND DRUG DISCOVERY FORUM

Tuesday, November 13 – Thursday, November 15, 2012 Hyatt Dulles – Executive Meeting Center 2300 Dulles Corner Blvd., Herndon, VA Near Dulles International Airport in the Washington DC area Panelists: Krystof Bankiewicz, MD PhD – University of California, San Francisco David Cox, MD PhD – Pfizer Tom Crawford, MD – Johns Hopkins Hospital Shyamal Desai, … Read More

EXAMINING CIRCUITRY AND POSSIBLE INFLAMMATION IN THE A-T BRAIN

With funding from the A-T Children’s Project and the Australian-based BrAshA-T organization, a team of researchers in Australia is using neuroimaging technology to learn more about abnormal circuitry and inflammation in the brains of A-T patients, possibly providing clues for therapeutic targets and uncovering imaging biomarkers for use in clinical trials. Stephen Rose, PhD, Kate … Read More

DRUG EXPERT JOINS A-TCP SCIENTIFIC ADVISORY BOARD

The A-T Children’s Project welcomes Dr. Philip LoGrasso to its Scientific Advisory Board. Dr. LoGrasso is a Professor in the Molecular Therapeutics Department and Senior Director of Drug Discovery in the Translational Research Institute within The Scripps Research Institute where he has been since 2005. He current serves on the Scientific Advisory Board for Envoy … Read More

BROOKHAVEN NATIONAL LAB CONDUCTS NEW BRAIN IMAGING STUDY THAT HOLDS PROMISE FOR A-T

With help from scientists who specialize in brain imaging, the A-T Children’s Project is seeking ways to treat the abnormal brain circuitry in ataxia-telangiectasia (A-T). For the first time, a comprehensive PET and fMRI study of the brains of adults with A-T has begun. PET stands for Positron Emission Tomography, and these scans give three … Read More

RECENT PUBLICATIONS LOOK AT G-TUBE SATISFACTION, CRITICAL CARE AND SURGICAL RISKS IN A-T PATIENTS

Three papers have been published recently in the scientific literature describing: 1) gastrostomy tube (G-tube) safety and satisfaction in patients with A-T; 2) the care of critically ill A-T patients and 3) the care of patients with A-T undergoing operations and the possible risks associated with the use of anesthesia for surgical procedures. G-Tube Placement … Read More

CALIFORNIA RESEARCHER CONTINUES DEVELOPMENT OF A CELL MODEL FOR A-T

The A-T Children’s Project has granted funding for Yang Xu, PhD from the University of California, San Diego to continue development of a stem cell-based model for A-T. This type of “disease-in-a-dish” model can be used to screen hundreds of thousands of compounds for their ability to diminish or reverse certain characteristics of the disease … Read More

YOUNG LSU INVESTIGATOR RECEIVES POST DOCTORAL FELLOWSHIP AWARD

Benjamin Siddoway, PhD from the Louisiana State University (LSU) Health Sciences Center is the first recipient of the A-T Children’s Project’s Post Doctoral Fellowship Award for his grant entitled “Addressing neurological dysfunction in A-T: Investigation into novel, physiologic ATM activation in neurons and ATM-PP1 signaling in reorganization and refinement of post synaptic architecture.” The A-T … Read More

TWO NEW RESEARCH PROJECTS TO FOCUS ON CELL DEATH AND CONSEQUENCES IN THE BRAIN

The A-T Children’s Project is funding two new research grants that may provide insights regarding brain function in A-T. The Florida-based Wobbly Feet Foundation has agreed to co-fund part of each grant in an on-going partnership to accelerate A-T research. Research for the first grant, entitled “Linking neurodegeneration to protein turnover in ataxia-telangiectasia,” will be … Read More